HBV Target gene Detail Information

> PPP1R1C Gene Search Result


Gene Information
Gene Name PPP1R1C
Gene ID 151242
Gene Full Name protein phosphatase 1 regulatory inhibitor subunit 1C
Gene Alias IPP5
Transcripts ENSG00000150722
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Golgi apparatus;Nucleoli;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q8WVI7
HGNC ID HGNC:14940
VEGA ID OTTHUMG00000154326
OMIM ID 613240
String ID 9606.ENSP00000280295
PharmGKB ID PA33640
Target gene [PPP1R1C] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003187 chr2 69 90 159 View
1008531 chr2 14 6 20 View
1008532 chr2 14 6 20 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PPP1R1C expression and immune infiltrating cell level correlation result in HBV+ samples
PPP1R1C expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).