HIV Target gene Detail Information

> PPP1R16A Gene Search Result

Gene Information

Gene Name	PPP1R16A
Gene ID	84988
Gene Full Name	protein phosphatase 1 regulatory subunit 16A
Gene Alias	MYPT3
Transcripts	ENSG00000160972
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q96I34
HGNC ID	HGNC:14941
VEGA ID	OTTHUMG00000165173
OMIM ID	609172
String ID	9606.ENSP00000292539
PharmGKB ID	PA33634

Target gene [PPP1R16A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002505	chr8	90	1		91	View
4004229	chr8	47			47	View
4004616	chr8	37	4		41	View
4014951	chr8	2			2	View
4015565	chr8	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PPP1R16A expression and immune infiltrating cell level correlation result in HIV+ samples
PPP1R16A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PPP1R16A expression and immune infiltrating cell level correlation result in HIV+ samples
PPP1R16A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).