HTLV1 Target gene Detail Information

> PPP1R15B Gene Search Result

Gene Information

Gene Name	PPP1R15B
Gene ID	84919
Gene Full Name	protein phosphatase 1 regulatory subunit 15B
Gene Alias	CREP; MSSGM2
Transcripts	ENSG00000158615
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q5SWA1
HGNC ID	HGNC:14951
VEGA ID	OTTHUMG00000036105
OMIM ID	613257
String ID	9606.ENSP00000356156
PharmGKB ID	PA33633

Target gene [PPP1R15B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000688	chr1	45	692	241	978	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of PPP1R15B expression and immune infiltrating cell level correlation result in HTLV1+ samples
PPP1R15B expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of PPP1R15B expression and immune infiltrating cell level correlation result in HTLV1+ samples
PPP1R15B expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of PPP1R15B expression and immune infiltrating cell level correlation result in HTLV1+ samples
PPP1R15B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).