HTLV1 Target gene Detail Information

> PPP1R13L Gene Search Result


Gene Information
Gene Name PPP1R13L
Gene ID 10848
Gene Full Name protein phosphatase 1 regulatory subunit 13 like
Gene Alias RAI; RAI4; IASPP; NKIP1
Transcripts ENSG00000104881
Virus HTLV1
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Gene Function Oncogene
Uniport_ID Q8WUF5
HGNC ID HGNC:18838
VEGA ID OTTHUMG00000181784
OMIM ID 607463
String ID 9606.ENSP00000403902
PharmGKB ID PA34195
Target gene [PPP1R13L] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6005379 chr19 83 6 89 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of PPP1R13L expression and immune infiltrating cell level correlation result in HTLV1+ samples
PPP1R13L expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of PPP1R13L expression and immune infiltrating cell level correlation result in HTLV1+ samples
PPP1R13L expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of PPP1R13L expression and immune infiltrating cell level correlation result in HTLV1+ samples
PPP1R13L expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).