HBV Target gene Detail Information

> PPP1R12B Gene Search Result

Gene Information

Gene Name	PPP1R12B
Gene ID	4660
Gene Full Name	protein phosphatase 1 regulatory subunit 12B
Gene Alias	MYPT2; PP1bp55
Transcripts	ENSG00000077157
Virus	HBV
Gene Type	protein coding
HPA Location Info	Actin filaments;Plasma membrane;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	O60237
HGNC ID	HGNC:7619
VEGA ID	OTTHUMG00000041393
OMIM ID	603768
String ID	9606.ENSP00000476755
PharmGKB ID	PA33618

Target gene [PPP1R12B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004909	chr1	59	7		66	View
1013327	chr1	2	3		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PPP1R12B expression and immune infiltrating cell level correlation result in HBV+ samples
PPP1R12B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).