HIV Target gene Detail Information

> PPP1R12A Gene Search Result

Gene Information

Gene Name	PPP1R12A
Gene ID	4659
Gene Full Name	protein phosphatase 1 regulatory subunit 12A
Gene Alias	MBS; M130; MYPT1
Transcripts	ENSG00000058272
Virus	HIV
Gene Type	protein coding
HPA Location Info	Actin filaments;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O14974
HGNC ID	HGNC:7618
VEGA ID	OTTHUMG00000170100
OMIM ID	602021
String ID	9606.ENSP00000389168
PharmGKB ID	PA33617

Target gene [PPP1R12A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005518	chr12	4	13	15	32	View
4005725	chr12	4	24	2	30	View
4015604	chr12	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PPP1R12A expression and immune infiltrating cell level correlation result in HIV+ samples
PPP1R12A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PPP1R12A expression and immune infiltrating cell level correlation result in HIV+ samples
PPP1R12A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).