HIV Target gene Detail Information

> PPP1R10 Gene Search Result

Gene Information

Gene Name	PPP1R10
Gene ID	5514
Gene Full Name	protein phosphatase 1 regulatory subunit 10
Gene Alias	p99; FB19; R111; CAT53; PNUTS; PP1R10
Transcripts	ENSG00000230995
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nuclear bodies;
HPA Protein Class Info	Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q96QC0
HGNC ID	HGNC:9284
VEGA ID	OTTHUMG00000004917
OMIM ID	603771
String ID	9606.ENSP00000365694
PharmGKB ID	PA33612

Target gene [PPP1R10] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4015824	chr6		1		1	View
4015825	chr6		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PPP1R10 expression and immune infiltrating cell level correlation result in HIV+ samples
PPP1R10 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PPP1R10 expression and immune infiltrating cell level correlation result in HIV+ samples
PPP1R10 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).