HIV Target gene Detail Information

> PPM1E Gene Search Result


Gene Information
Gene Name PPM1E
Gene ID 22843
Gene Full Name protein phosphatase, Mg2+/Mn2+ dependent 1E
Gene Alias POPX1; PP2CH; caMKN; CaMKP-N
Transcripts ENSG00000175175
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoli;Nucleoplasm;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q8WY54
HGNC ID HGNC:19322
VEGA ID OTTHUMG00000179248
OMIM ID 619308
String ID 9606.ENSP00000312411
PharmGKB ID PA134943567
Target gene [PPM1E] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4011835 chr17 2 4 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of PPM1E expression and immune infiltrating cell level correlation result in HIV+ samples
PPM1E expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).