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HBV Target gene Detail Information

> PPFIA1 Gene Search Result


Gene Information
Gene Name PPFIA1
Gene ID 8500
Gene Full Name PTPRF interacting protein alpha 1
Gene Alias LIP1; LIP.1; LIPRIN
Transcripts ENSG00000288198
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Focal adhesion sites;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q13136
HGNC ID HGNC:9245
VEGA ID OTTHUMG00000167266
OMIM ID 611054
String ID 9606.ENSP00000253925
PharmGKB ID PA33566
Target gene [PPFIA1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003281 chr11 139 10 149 View
1003447 chr11 123 10 133 View
1010052 chr11 11 2 13 View
1401631 chr11 11 2 13 View
1401632 chr11 123 10 133 View
1401633 chr11 139 10 149 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PPFIA1 expression and immune infiltrating cell level correlation result in HBV+ samples
PPFIA1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).