HBV Target gene Detail Information

> PPARGC1A Gene Search Result

Gene Information

Gene Name	PPARGC1A
Gene ID	10891
Gene Full Name	PPARG coactivator 1 alpha
Gene Alias	LEM6; PGC1; PGC1A; PGC-1v; PPARGC1; PGC-1alpha; PGC-1(alpha)
Transcripts	ENSG00000109819
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins
Uniport_ID	Q9UBK2
HGNC ID	HGNC:9237
VEGA ID	OTTHUMG00000097747
OMIM ID	604517
String ID	9606.ENSP00000264867
PharmGKB ID	PA33558

Target gene [PPARGC1A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006501	chr4	7	3	27	37	View
1007859	chr4	15	7	2	24	View
1009079	chr4	16	1		17	View
1009394	chr4	9	2	5	16	View
1009395	chr4	9	2	5	16	View
1010514	chr4	8	4		12	View
1010982	chr4	3	7		10	View
1015986	chr4	2			2	View
1017308	chr4	1			1	View
1400057	chr4	7	2		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PPARGC1A expression and immune infiltrating cell level correlation result in HBV+ samples
PPARGC1A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).