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HBV Target gene Detail Information

> PPARG Gene Search Result


Gene Information
Gene Name PPARG
Gene ID 5468
Gene Full Name peroxisome proliferator activated receptor gamma
Gene Alias GLM1; CIMT1; NR1C3; PPARG1; PPARG2; PPARgamma
Transcripts ENSG00000132170
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Vesicles;
HPA Protein Class Info Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors
Gene Function Suppressor gene & Oncogene
Uniport_ID P37231
HGNC ID HGNC:9236
VEGA ID OTTHUMG00000129764
OMIM ID 601487
String ID 9606.ENSP00000287820
Drugbank ID BE0000215
PharmGKB ID PA281
Target gene [PPARG] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1019843 chr3 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PPARG expression and immune infiltrating cell level correlation result in HBV+ samples
PPARG expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).