HBV Target gene Detail Information

> POU6F1 Gene Search Result


Gene Information
Gene Name POU6F1
Gene ID 5463
Gene Full Name POU class 6 homeobox 1
Gene Alias BRN5; MPOU; TCFB1
Transcripts ENSG00000184271
Virus HBV
Gene Type protein coding
HPA Location Info Nuclear bodies;Actin filaments;
HPA Protein Class Info Predicted intracellular proteins
HGNC ID HGNC:9224
VEGA ID OTTHUMG00000169622
OMIM ID 618043
String ID 9606.ENSP00000373895
PharmGKB ID PA33548
Target gene [POU6F1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004844 chr12 30 16 21 67 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of POU6F1 expression and immune infiltrating cell level correlation result in HBV+ samples
POU6F1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).