HBV Target gene Detail Information

> POU2F3 Gene Search Result

Gene Information

Gene Name	POU2F3
Gene ID	25833
Gene Full Name	POU class 2 homeobox 3
Gene Alias	PLA1; OCT11; PLA-1; Epoc-1; OCT-11; OTF-11; Skn-1a
Transcripts	ENSG00000137709
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;Nuclear bodies;Nucleoli;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Gene Function	Suppressor gene
Uniport_ID	Q9UKI9
HGNC ID	HGNC:19864
VEGA ID	OTTHUMG00000166140
OMIM ID	607394
String ID	9606.ENSP00000260264
PharmGKB ID	PA134963258

Target gene [POU2F3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001565	chr11	159	139	324	622	View
1004670	chr11	63	8	2	73	View
1005656	chr11	33	9	8	50	View
1404422	chr11			1	1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of POU2F3 expression and immune infiltrating cell level correlation result in HBV+ samples
POU2F3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).