HBV Target gene Detail Information

> POU2F2 Gene Search Result


Gene Information
Gene Name POU2F2
Gene ID 5452
Gene Full Name POU class 2 homeobox 2
Gene Alias OCT2; OTF2; Oct-2
Transcripts ENSG00000028277
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Vesicles;
HPA Protein Class Info Cancer-related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID P09086
HGNC ID HGNC:9213
VEGA ID OTTHUMG00000165991
OMIM ID 164176
String ID 9606.ENSP00000431603
Drugbank ID BE0004821
PharmGKB ID PA33537
Target gene [POU2F2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005238 chr19 20 23 15 58 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of POU2F2 expression and immune infiltrating cell level correlation result in HBV+ samples
POU2F2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).