HTLV1 Target gene Detail Information

> POMGNT1 Gene Search Result

Gene Information

Gene Name	POMGNT1
Gene ID	55624
Gene Full Name	protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
Gene Alias	MEB; RP76; GNTI.2; LGMD2O; GnT I.2; LGMDR15; MGAT1.2; gnT-I.2
Transcripts	ENSG00000085998
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted membrane proteins
Uniport_ID	Q8WZA1
HGNC ID	HGNC:19139
VEGA ID	OTTHUMG00000007604
OMIM ID	606822
String ID	9606.ENSP00000361060
PharmGKB ID	PA142671161

Target gene [POMGNT1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6015709	chr1	9	1	3	13	View
6019189	chr1	4	4		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of POMGNT1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
POMGNT1 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of POMGNT1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
POMGNT1 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of POMGNT1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
POMGNT1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).