HIV Target gene Detail Information

> POLR2F Gene Search Result

Gene Information

Gene Name	POLR2F
Gene ID	5435
Gene Full Name	RNA polymerase II subunit F
Gene Alias	RPB6; POLRF; RPC15; RPABC2; RPB14.4; HRBP14.4; RPABC14.4
Transcripts	ENSG00000100142
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli fibrillar center;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, RNA polymerase related proteins
Uniport_ID	P61218
HGNC ID	HGNC:9193
VEGA ID	OTTHUMG00000151160
OMIM ID	604414
String ID	9606.ENSP00000403852
PharmGKB ID	PA33513

Target gene [POLR2F] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000460	chr22	445	2		447	View
4012652	chr22	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of POLR2F expression and immune infiltrating cell level correlation result in HIV+ samples
POLR2F expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of POLR2F expression and immune infiltrating cell level correlation result in HIV+ samples
POLR2F expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).