HIV Target gene Detail Information

> POLN Gene Search Result

Gene Information

Gene Name	POLN
Gene ID	353497
Gene Full Name	DNA polymerase nu
Gene Alias	POL4P
Transcripts	ENSG00000130997
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q7Z5Q5
HGNC ID	HGNC:18870
VEGA ID	OTTHUMG00000090081
OMIM ID	610887
String ID	9606.ENSP00000435506
PharmGKB ID	PA134979866

Target gene [POLN] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011398	chr4	7			7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of POLN expression and immune infiltrating cell level correlation result in HIV+ samples
POLN expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).