HIV Target gene Detail Information

> POLK Gene Search Result

Gene Information

Gene Name	POLK
Gene ID	51426
Gene Full Name	DNA polymerase kappa
Gene Alias	DINP; POLQ; DINB1
Transcripts	ENSG00000122008
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9UBT6
HGNC ID	HGNC:9183
VEGA ID	OTTHUMG00000102107
OMIM ID	605650
String ID	9606.ENSP00000241436
Drugbank ID	BE0003870
PharmGKB ID	PA33503

Target gene [POLK] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001142	chr5	161	38	7	206	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of POLK expression and immune infiltrating cell level correlation result in HIV+ samples
POLK expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).