HIV Target gene Detail Information

> POLI Gene Search Result

Gene Information

Gene Name	POLI
Gene ID	11201
Gene Full Name	DNA polymerase iota
Gene Alias	eta2; RAD30B; RAD3OB
Transcripts	ENSG00000101751
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Cytoplasmic bodies;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q9UNA4
HGNC ID	HGNC:9182
VEGA ID	OTTHUMG00000132704
OMIM ID	605252
String ID	9606.ENSP00000462664
PharmGKB ID	PA33502

Target gene [POLI] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013454	chr18	1	1	1	3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of POLI expression and immune infiltrating cell level correlation result in HIV+ samples
POLI expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).