HIV Target gene Detail Information

> POGZ Gene Search Result

Gene Information

Gene Name	POGZ
Gene ID	23126
Gene Full Name	pogo transposable element derived with ZNF domain
Gene Alias	MRD37; WHSUS; ZNF635; ZNF280E; ZNF635m
Transcripts	ENSG00000143442
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q7Z3K3
HGNC ID	HGNC:18801
VEGA ID	OTTHUMG00000012499
OMIM ID	614787
String ID	9606.ENSP00000271715
PharmGKB ID	PA38685

Target gene [POGZ] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004322	chr1	34	11	1	46	View
4009719	chr1	10	1		11	View
4009720	chr1	10	1		11	View
4009721	chr1	10	1		11	View
4009722	chr1	10	1		11	View
4009723	chr1	10	1		11	View
4011546	chr1	4	2		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of POGZ expression and immune infiltrating cell level correlation result in HIV+ samples
POGZ expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of POGZ expression and immune infiltrating cell level correlation result in HIV+ samples
POGZ expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).