HTLV1 Target gene Detail Information

> POGK Gene Search Result

Gene Information

Gene Name	POGK
Gene ID	57645
Gene Full Name	pogo transposable element derived with KRAB domain
Gene Alias	BASS2; KRBOX2; LST003
Transcripts	ENSG00000143157
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9P215
HGNC ID	HGNC:18800
VEGA ID	OTTHUMG00000034325
String ID	9606.ENSP00000356849
PharmGKB ID	PA38684

Target gene [POGK] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6002319	chr1	147	91	17	255	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of POGK expression and immune infiltrating cell level correlation result in HTLV1+ samples
POGK expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of POGK expression and immune infiltrating cell level correlation result in HTLV1+ samples
POGK expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of POGK expression and immune infiltrating cell level correlation result in HTLV1+ samples
POGK expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).