HBV Target gene Detail Information

> POF1B Gene Search Result


Gene Information
Gene Name POF1B
Gene ID 79983
Gene Full Name POF1B, actin binding protein
Gene Alias POF; POF2B
Transcripts ENSG00000124429
Virus HBV
Gene Type protein coding
HPA Location Info Golgi apparatus;Nucleoplasm;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q8WVV4
HGNC ID HGNC:13711
VEGA ID OTTHUMG00000021934
OMIM ID 300603
String ID 9606.ENSP00000262753
PharmGKB ID PA134937695
Target gene [POF1B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1404405 chrX 4 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of POF1B expression and immune infiltrating cell level correlation result in HBV+ samples
POF1B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).