Home
Virus
Gene
Disease
Dataset
Download
Help
 
HTLV1 Target gene Detail Information

> PNPLA8 Gene Search Result


Gene Information
Gene Name PNPLA8
Gene ID 50640
Gene Full Name patatin like phospholipase domain containing 8
Gene Alias MMLA; IPLA2G; IPLA2-2; iPLA2gamma; PNPLA-gamma
Transcripts ENSG00000135241
Virus HTLV1
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;Golgi apparatus;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q9NP80
HGNC ID HGNC:28900
VEGA ID OTTHUMG00000154870
OMIM ID 612123
String ID 9606.ENSP00000410804
PharmGKB ID PA145148236
Target gene [PNPLA8] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6011334 chr7 26 1 27 View
6020015 chr7 3 4 7 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of PNPLA8 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PNPLA8 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of PNPLA8 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PNPLA8 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of PNPLA8 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PNPLA8 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).