HTLV1 Target gene Detail Information

> PNPLA7 Gene Search Result

Gene Information

Gene Name	PNPLA7
Gene ID	375775
Gene Full Name	patatin like phospholipase domain containing 7
Gene Alias	NTEL1; NTE-R1; C9orf111
Transcripts	ENSG00000130653
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;Centriolar satellite;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q6ZV29
HGNC ID	HGNC:24768
VEGA ID	OTTHUMG00000020990
OMIM ID	612122
String ID	9606.ENSP00000384610
PharmGKB ID	PA134935962

Target gene [PNPLA7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6007386	chr9	48	5	3	56	View
6022220	chr9	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of PNPLA7 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PNPLA7 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of PNPLA7 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PNPLA7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).