Home
Virus
Gene
Disease
Dataset
Download
Help
 
HIV Target gene Detail Information

> PNPLA6 Gene Search Result


Gene Information
Gene Name PNPLA6
Gene ID 10908
Gene Full Name patatin like phospholipase domain containing 6
Gene Alias NTE; sws; BNHS; LNMS; OMCS; SPG39; NTEMND; iPLA2delta
Transcripts ENSG00000032444
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Endoplasmic reticulum;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q8IY17
HGNC ID HGNC:16268
VEGA ID OTTHUMG00000182094
OMIM ID 603197
String ID 9606.ENSP00000407509
PharmGKB ID PA145148268
Target gene [PNPLA6] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4014178 chr19 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of PNPLA6 expression and immune infiltrating cell level correlation result in HIV+ samples
PNPLA6 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of PNPLA6 expression and immune infiltrating cell level correlation result in HIV+ samples
PNPLA6 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).