HTLV1 Target gene Detail Information

> PNLIP Gene Search Result

Gene Information

Gene Name	PNLIP
Gene ID	5406
Gene Full Name	pancreatic lipase
Gene Alias	PL; PTL; PNLIPD
Transcripts	ENSG00000175535
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins
Uniport_ID	P16233
HGNC ID	HGNC:9155
VEGA ID	OTTHUMG00000019103
OMIM ID	246600
String ID	9606.ENSP00000358223
Drugbank ID	BE0000683
PharmGKB ID	PA33478

Target gene [PNLIP] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6009926	chr10	14	20		34	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of PNLIP expression and immune infiltrating cell level correlation result in HTLV1+ samples
PNLIP expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of PNLIP expression and immune infiltrating cell level correlation result in HTLV1+ samples
PNLIP expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of PNLIP expression and immune infiltrating cell level correlation result in HTLV1+ samples
PNLIP expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).