HIV Target gene Detail Information

> PNISR Gene Search Result

Gene Information

Gene Name	PNISR
Gene ID	25957
Gene Full Name	PNN interacting serine and arginine rich protein
Gene Alias	SFRS18; HSPC306; SRrp130; C6orf111; bA98I9.2
Transcripts	ENSG00000132424
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Cytosol;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8TF01
HGNC ID	HGNC:21222
VEGA ID	OTTHUMG00000015262
OMIM ID	616653
String ID	9606.ENSP00000358242
PharmGKB ID	PA162402984

Target gene [PNISR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4016401	chr6				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PNISR expression and immune infiltrating cell level correlation result in HIV+ samples
PNISR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).