HIV Target gene Detail Information

> PMPCA Gene Search Result

Gene Information

Gene Name	PMPCA
Gene ID	23203
Gene Full Name	peptidase, mitochondrial processing alpha subunit
Gene Alias	CLA1; CPD3; P-55; SCAR2; INPP5E; Alpha-MPP
Transcripts	ENSG00000165688
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q10713
HGNC ID	HGNC:18667
VEGA ID	OTTHUMG00000020926
OMIM ID	613036
String ID	9606.ENSP00000360782
PharmGKB ID	PA38629

Target gene [PMPCA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003647	chr9	53	3	1	57	View
4004272	chr9	40	6		46	View
4300065	chr9				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PMPCA expression and immune infiltrating cell level correlation result in HIV+ samples
PMPCA expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PMPCA expression and immune infiltrating cell level correlation result in HIV+ samples
PMPCA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).