HIV Target gene Detail Information

> PMEL Gene Search Result

Gene Information

Gene Name	PMEL
Gene ID	6490
Gene Full Name	premelanosome protein
Gene Alias	P1; SI; SIL; ME20; P100; SILV; ME20M; gp100; ME20-M; PMEL17; D12S53E
Transcripts	ENSG00000185664
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;Golgi apparatus;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P40967
HGNC ID	HGNC:10880
VEGA ID	OTTHUMG00000170573
OMIM ID	155550
String ID	9606.ENSP00000402758
PharmGKB ID	PA35781

Target gene [PMEL] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007533	chr12	19			19	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PMEL expression and immune infiltrating cell level correlation result in HIV+ samples
PMEL expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).