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HBV Target gene Detail Information

> PLXNB2 Gene Search Result


Gene Information
Gene Name PLXNB2
Gene ID 23654
Gene Full Name plexin B2
Gene Alias MM1; PLEXB2; Nbla00445; dJ402G11.3
Transcripts ENSG00000196576
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID O15031
HGNC ID HGNC:9104
VEGA ID OTTHUMG00000150219
OMIM ID 604293
String ID 9606.ENSP00000409171
PharmGKB ID PA33430
Target gene [PLXNB2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000224 chr22 2369 1169 577 4115 View
1000263 chr22 2388 790 423 3601 View
1000872 chr22 1308 15 1 1324 View
1000873 chr22 1308 15 1 1324 View
1000875 chr22 1308 15 1 1324 View
1020011 chr22 0 View
1400620 chr22 1308 15 1 1324 View
1402256 chr22 1308 15 1 1324 View
1404299 chr22 1305 14 1 1320 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of PLXNB2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
PLXNB2 expression: Low -> High
Lollipop of PLXNB2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of PLXNB2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PLXNB2 expression and immune infiltrating cell level correlation result in HBV+ samples
PLXNB2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).