HIV Target gene Detail Information

> PLGLB1 Gene Search Result

Gene Information

Gene Name	PLGLB1
Gene ID	5343
Gene Full Name	plasminogen-like B1
Gene Alias	PLGL; PRGB; PLGP1; PRP-B
Transcripts	ENSG00000183281
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted secreted proteins
Uniport_ID	Q02325
HGNC ID	HGNC:9072
VEGA ID	OTTHUMG00000154612
OMIM ID	173340
String ID	9606.ENSP00000347933
PharmGKB ID	PA33406

Target gene [PLGLB1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4014930	chr2	2			2	View
4100004	chr2				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PLGLB1 expression and immune infiltrating cell level correlation result in HIV+ samples
PLGLB1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).