HBV Target gene Detail Information

> PLEKHA6 Gene Search Result

Gene Information

Gene Name	PLEKHA6
Gene ID	22874
Gene Full Name	pleckstrin homology domain containing A6
Gene Alias	PEPP3; PEPP-3
Transcripts	ENSG00000143850
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cell Junctions;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9Y2H5
HGNC ID	HGNC:17053
VEGA ID	OTTHUMG00000036057
OMIM ID	607771
String ID	9606.ENSP00000272203
PharmGKB ID	PA134955964

Target gene [PLEKHA6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001669	chr1	151	205	179	535	View
1002530	chr1	240	7	8	255	View
1400112	chr1	3	3		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PLEKHA6 expression and immune infiltrating cell level correlation result in HBV+ samples
PLEKHA6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).