HIV Target gene Detail Information

> PLEC Gene Search Result


Gene Information
Gene Name PLEC
Gene ID 5339
Gene Full Name plectin
Gene Alias HD1; PCN; EBS1; EBSO; PLTN; EBSMD; EBSND; EBSOG; EBSPA; PLEC1; LGMD2Q; PLEC1b; LGMDR17
Transcripts ENSG00000178209
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Intermediate filaments;Focal adhesion sites;
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q15149
HGNC ID HGNC:9069
VEGA ID OTTHUMG00000165291
OMIM ID 601282
String ID 9606.ENSP00000323856
PharmGKB ID PA33399
Target gene [PLEC] related to VISs
DVIDChromosomeHMTFBSCASum of Overlapped RecordsDetail
4000769 chr8 28 245 13 286 View
4000911 chr8 51 98 101 250 View
4001375 chr8 65 69 38 172 View
4002923 chr8 9 61 5 75 View
4003212 chr8 60 6 66 View
4003465 chr8 52 3 6 61 View
4005080 chr8 5 31 36 View
4005367 chr8 29 1 30 View
4005581 chr8 31 31 View
4006902 chr8 21 1 22 View
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Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of PLEC expression and immune infiltrating cell level correlation result in HIV+ samples
PLEC expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).