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EBV Target gene Detail Information

> PLD1 Gene Search Result


Gene Information
Gene Name PLD1
Gene ID 5337
Gene Full Name phospholipase D1
Gene Alias CVDD
Transcripts ENSG00000075651
Virus EBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins
Gene Function Suppressor gene
Uniport_ID Q13393
HGNC ID HGNC:9067
VEGA ID OTTHUMG00000156947
OMIM ID 602382
String ID 9606.ENSP00000342793
Drugbank ID BE0002181
PharmGKB ID PA164742228
Target gene [PLD1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
3000080 chr3 152 68 23 243 View
3000906 chr8 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE102203 (GEO) B-cell lymphoma 9 Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE100458 (GEO) Burkitt lymphoma 14 Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO) Burkitt lymphoma 12 Burkitt lymphoma cell line Awia (EBV+)(12)
GSE135644 (GEO) Gastric carcinoma 10 Gastric adenocarcinoma cell line AGS (5), Gastric adenocarcinoma cell line AGS (EBV+)(5)
GSE45919 (GEO) Infectious mononucleosis 24 Infectious mononucleosis (IM)(EBV+)(3), Normal (9), Latent EBV (12)
GSE85599 (GEO) Infectious mononucleosis 17 Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE58240 (GEO) Multiple sclerosis 32 Multiple sclerosis IFN-β treated (EBV+)(16), Multiple sclerosis untreated (EBV+)(16)
GSE12452 (GEO) Nasopharyngeal carcinoma 41 Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE102203

HeatMap of cell type fractions in all samples Lollipop of PLD1 expression and immune infiltrating cell level correlation result in EBV+ samples
PLD1 expression: Low -> High

> Dataset: GSE100458

HeatMap of cell type fractions in all samples Lollipop of PLD1 expression and immune infiltrating cell level correlation result in EBV+ samples
PLD1 expression: Low -> High

> Dataset: GSE42867

HeatMap of cell type fractions in all samples Lollipop of PLD1 expression and immune infiltrating cell level correlation result in EBV+ samples
PLD1 expression: Low -> High

> Dataset: GSE135644

HeatMap of cell type fractions in all samples Lollipop of PLD1 expression and immune infiltrating cell level correlation result in EBV+ samples
PLD1 expression: Low -> High

> Dataset: GSE45919

HeatMap of cell type fractions in all samples Lollipop of PLD1 expression and immune infiltrating cell level correlation result in EBV+ samples
PLD1 expression: Low -> High

> Dataset: GSE85599

HeatMap of cell type fractions in all samples Lollipop of PLD1 expression and immune infiltrating cell level correlation result in EBV+ samples
PLD1 expression: Low -> High

> Dataset: GSE58240

HeatMap of cell type fractions in all samples Lollipop of PLD1 expression and immune infiltrating cell level correlation result in EBV+ samples
PLD1 expression: Low -> High

> Dataset: GSE12452

HeatMap of cell type fractions in all samples Lollipop of PLD1 expression and immune infiltrating cell level correlation result in EBV+ samples
PLD1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).