HIV Target gene Detail Information

> PLB1 Gene Search Result

Gene Information

Gene Name	PLB1
Gene ID	151056
Gene Full Name	phospholipase B1
Gene Alias	PLB; PLB/LIP
Transcripts	ENSG00000163803
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q6P1J6
HGNC ID	HGNC:30041
VEGA ID	OTTHUMG00000152014
OMIM ID	610179
String ID	9606.ENSP00000330442
PharmGKB ID	PA134891309

Target gene [PLB1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4012597	chr2	3	2		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PLB1 expression and immune infiltrating cell level correlation result in HIV+ samples
PLB1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).