HIV Target gene Detail Information

> PLA2R1 Gene Search Result

Gene Information

Gene Name	PLA2R1
Gene ID	22925
Gene Full Name	phospholipase A2 receptor 1
Gene Alias	PLA2R; PLA2-R; PLA2IR; CLEC13C; PLA2G1R
Transcripts	ENSG00000153246
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Predicted to be secreted;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins, Predicted secreted proteins
Gene Function	Suppressor gene
Uniport_ID	Q13018
HGNC ID	HGNC:9042
VEGA ID	OTTHUMG00000154087
OMIM ID	604939
String ID	9606.ENSP00000283243
PharmGKB ID	PA33369

Target gene [PLA2R1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002489	chr2	92			92	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PLA2R1 expression and immune infiltrating cell level correlation result in HIV+ samples
PLA2R1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).