HBV Target gene Detail Information

> PLA2G4C Gene Search Result

Gene Information

Gene Name	PLA2G4C
Gene ID	8605
Gene Full Name	phospholipase A2 group IVC
Gene Alias	CPLA2-gamma
Transcripts	ENSG00000105499
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID	Q9UP65
HGNC ID	HGNC:9037
VEGA ID	OTTHUMG00000183185
OMIM ID	603602
String ID	9606.ENSP00000472546
PharmGKB ID	PA33365

Target gene [PLA2G4C] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005545	chr19	25	26	1	52	View
1010683	chr19	11			11	View
1013905	chr19	3	1		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PLA2G4C expression and immune infiltrating cell level correlation result in HBV+ samples
PLA2G4C expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).