HBV Target gene Detail Information

> PLA2G4A Gene Search Result

Gene Information

Gene Name	PLA2G4A
Gene ID	5321
Gene Full Name	phospholipase A2 group IVA
Gene Alias	cPLA2; PLA2G4; cPLA2-alpha
Transcripts	ENSG00000116711
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Vesicles;
HPA Protein Class Info	Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID	P47712
HGNC ID	HGNC:9035
VEGA ID	OTTHUMG00000035512
OMIM ID	600522
String ID	9606.ENSP00000356436
Drugbank ID	BE0000657
PharmGKB ID	PA271

Target gene [PLA2G4A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1015783	chr1	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PLA2G4A expression and immune infiltrating cell level correlation result in HBV+ samples
PLA2G4A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).