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HTLV1 Target gene Detail Information

> PKN3 Gene Search Result


Gene Information
Gene Name PKN3
Gene ID 29941
Gene Full Name protein kinase N3
Gene Alias UTDP4-1
Transcripts ENSG00000160447
Virus HTLV1
Gene Type protein coding
HPA Location Info Vesicles;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q6P5Z2
HGNC ID HGNC:17999
VEGA ID OTTHUMG00000020757
OMIM ID 610714
String ID 9606.ENSP00000291906
PharmGKB ID PA134919098
Target gene [PKN3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6012679 chr9 21 21 View
6012689 chr9 21 21 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of PKN3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PKN3 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of PKN3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PKN3 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of PKN3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PKN3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).