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HTLV1 Target gene Detail Information

> PKD2L1 Gene Search Result


Gene Information
Gene Name PKD2L1
Gene ID 9033
Gene Full Name polycystin 2 like 1, transient receptor potential cation channel
Gene Alias PCL; PKDL; PKD2L; TRPP3
Transcripts ENSG00000107593
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID Q9P0L9
HGNC ID HGNC:9011
VEGA ID OTTHUMG00000018910
OMIM ID 604532
String ID 9606.ENSP00000325296
Drugbank ID BE0008849
PharmGKB ID PA33344
Target gene [PKD2L1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6016289 chr10 11 1 12 View
6024518 chr10 3 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of PKD2L1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PKD2L1 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of PKD2L1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PKD2L1 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of PKD2L1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PKD2L1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).