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HTLV1 Target gene Detail Information

> PKD1 Gene Search Result


Gene Information
Gene Name PKD1
Gene ID 5310
Gene Full Name polycystin 1, transient receptor potential channel interacting
Gene Alias PBP; PC1; Pc-1; TRPP1
Transcripts ENSG00000008710
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Gene Function Suppressor gene
Uniport_ID P98161
HGNC ID HGNC:9008
VEGA ID OTTHUMG00000155795
OMIM ID 601313
String ID 9606.ENSP00000262304
PharmGKB ID PA35521
Target gene [PKD1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6017854 chr16 10 10 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of PKD1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PKD1 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of PKD1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PKD1 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of PKD1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PKD1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).