HIV Target gene Detail Information

> PIP4K2B Gene Search Result

Gene Information

Gene Name	PIP4K2B
Gene ID	8396
Gene Full Name	phosphatidylinositol-5-phosphate 4-kinase type 2 beta
Gene Alias	PI5P4KB; PIP5K2B; PIP5KIIB; PIP5P4KB; PIP5KIIbeta
Transcripts	ENSG00000277292
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Enzymes, Predicted intracellular proteins
Uniport_ID	P78356
HGNC ID	HGNC:8998
OMIM ID	603261
String ID	9606.ENSP00000482548
Drugbank ID	BE0009471; BE0009517
PharmGKB ID	PA162399640

Target gene [PIP4K2B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004416	chr17	27	14	3	44	View
4011455	chr17		7		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PIP4K2B expression and immune infiltrating cell level correlation result in HIV+ samples
PIP4K2B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PIP4K2B expression and immune infiltrating cell level correlation result in HIV+ samples
PIP4K2B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).