HIV Target gene Detail Information

> PIP4K2A Gene Search Result

Gene Information

Gene Name	PIP4K2A
Gene ID	5305
Gene Full Name	phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
Gene Alias	PIPK; PI5P4KA; PIP5K2A; PIP5KIIA; PIP5KII-alpha
Transcripts	ENSG00000150867
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Cytosol;Plasma membrane;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P48426
HGNC ID	HGNC:8997
VEGA ID	OTTHUMG00000017810
OMIM ID	603140
String ID	9606.ENSP00000365757
PharmGKB ID	PA162399615

Target gene [PIP4K2A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003552	chr10	25	33	1	59	View
4004670	chr10	1	5	35	41	View
4005218	chr10	1	5	29	35	View
4006294	chr10		4	22	26	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PIP4K2A expression and immune infiltrating cell level correlation result in HIV+ samples
PIP4K2A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PIP4K2A expression and immune infiltrating cell level correlation result in HIV+ samples
PIP4K2A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).