HBV Target gene Detail Information

> PIK3R3 Gene Search Result

Gene Information

Gene Name	PIK3R3
Gene ID	8503
Gene Full Name	phosphoinositide-3-kinase regulatory subunit 3
Gene Alias	p55; p55PIK; p55-GAMMA
Transcripts	ENSG00000117461
Virus	HBV
Gene Type	protein coding
HPA Location Info	Vesicles;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID	Q92569
HGNC ID	HGNC:8981
VEGA ID	OTTHUMG00000008096
OMIM ID	606076
String ID	9606.ENSP00000262741
Drugbank ID	BE0002384
PharmGKB ID	PA33314

Target gene [PIK3R3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009592	chr1	6	9		15	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PIK3R3 expression and immune infiltrating cell level correlation result in HBV+ samples
PIK3R3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).