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HBV Target gene Detail Information

> PIK3CD Gene Search Result


Gene Information
Gene Name PIK3CD
Gene ID 5293
Gene Full Name phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Gene Alias APDS; PI3K; IMD14; p110D; P110DELTA
Transcripts ENSG00000171608
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;Cytokinetic bridge;
HPA Protein Class Info Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID O00329
HGNC ID HGNC:8977
VEGA ID OTTHUMG00000001450
OMIM ID 602839
String ID 9606.ENSP00000366563
Drugbank ID BE0002406
Drug (Cytoscape Annotation) Idelalisib
PharmGKB ID PA33310
FDA Approved Drug Duvelisib
Target gene [PIK3CD] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004635 chr1 49 11 14 74 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PIK3CD expression and immune infiltrating cell level correlation result in HBV+ samples
PIK3CD expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).