HBV Target gene Detail Information

> PIK3CB Gene Search Result


Gene Information
Gene Name PIK3CB
Gene ID 5291
Gene Full Name phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
Gene Alias PI3K; PIK3C1; P110BETA; PI3KBETA
Transcripts ENSG00000051382
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Midbody;Nucleoli;Vesicles;
HPA Protein Class Info Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID P42338
HGNC ID HGNC:8976
VEGA ID OTTHUMG00000159893
OMIM ID 602925
String ID 9606.ENSP00000289153
Drugbank ID BE0002407
Drug (Cytoscape Annotation) Idelalisib
PharmGKB ID PA33309
FDA Approved Drug Alpelisib
Target gene [PIK3CB] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1014579 chr3 2 1 3 View
1015406 chr3 2 2 View
1017271 chr3 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PIK3CB expression and immune infiltrating cell level correlation result in HBV+ samples
PIK3CB expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).