HIV Target gene Detail Information

> PIK3CA Gene Search Result


Gene Information
Gene Name PIK3CA
Gene ID 5290
Gene Full Name phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Gene Alias MCM; CWS5; MCAP; PI3K; CLAPO; CLOVE; MCMTC; PI3K-alpha; p110-alpha
Transcripts ENSG00000121879
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Mitochondria;
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins
Gene Function Oncogene
Uniport_ID P42336
HGNC ID HGNC:8975
VEGA ID OTTHUMG00000157311
OMIM ID 171834
String ID 9606.ENSP00000263967
Drugbank ID BE0002379
PharmGKB ID PA33308
FDA Approved Drug Alpelisib
Target gene [PIK3CA] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4011254 chr3 7 7 View

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).