HIV Target gene Detail Information

> PIK3C3 Gene Search Result

Gene Information

Gene Name	PIK3C3
Gene ID	5289
Gene Full Name	phosphatidylinositol 3-kinase catalytic subunit type 3
Gene Alias	VPS34; Vps34; hVps34
Transcripts	ENSG00000078142
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q8NEB9
HGNC ID	HGNC:8974
VEGA ID	OTTHUMG00000132593
OMIM ID	602609
String ID	9606.ENSP00000262039
Drugbank ID	BE0003729
PharmGKB ID	PA33307

Target gene [PIK3C3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003139	chr18	27	29	13	69	View
4011137	chr18	7			7	View
4012267	chr18	1	4		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PIK3C3 expression and immune infiltrating cell level correlation result in HIV+ samples
PIK3C3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PIK3C3 expression and immune infiltrating cell level correlation result in HIV+ samples
PIK3C3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).