HTLV1 Target gene Detail Information

> PIH1D1 Gene Search Result

Gene Information

Gene Name	PIH1D1
Gene ID	55011
Gene Full Name	PIH1 domain containing 1
Gene Alias	Pih1; NOP17
Transcripts	ENSG00000104872
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9NWS0
HGNC ID	HGNC:26075
VEGA ID	OTTHUMG00000183167
OMIM ID	611480
String ID	9606.ENSP00000262265
PharmGKB ID	PA162399535

Target gene [PIH1D1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6004691	chr19	88	19		107	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of PIH1D1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PIH1D1 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of PIH1D1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PIH1D1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).