HIV Target gene Detail Information

> PIGX Gene Search Result

Gene Information

Gene Name	PIGX
Gene ID	54965
Gene Full Name	phosphatidylinositol glycan anchor biosynthesis class X
Gene Alias	PIG-X
Transcripts	ENSG00000163964
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q8TBF5
HGNC ID	HGNC:26046
VEGA ID	OTTHUMG00000155535
OMIM ID	610276
String ID	9606.ENSP00000296333
PharmGKB ID	PA134928970

Target gene [PIGX] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003917	chr3	47	5		52	View
4011614	chr3	2	4		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PIGX expression and immune infiltrating cell level correlation result in HIV+ samples
PIGX expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PIGX expression and immune infiltrating cell level correlation result in HIV+ samples
PIGX expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).